Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Current Topics in Virology   Volumes    Volume 1 
Bovine leukemia virus as a model for human T-cell leukemia virus
L. Willems, A. Burny, O. Dangoisse, D. Collete, F. Dequiedt, J. S. Gatot, P. Kerkhofs, L. Lefèbvre, C. Merezak, D. Portetelle, J. C. Twizere, R. Kettmann
Pages: 139 - 167
Number of pages: 29
Current Topics in Virology
Volume 1 

Copyright © 1999 Research Trends. All rights reserved


They are two kinds of experimental strategies to study the pathologies associated with human T-cell leukaemia virus (HTLV-I). The first one is based on the analysis of the HTLV virus itself within different species: rabbits, mice, rats and monkeys have been used for this purpose. The other approach is based on the understanding of diseases induced by viruses closely related to HTLV-I, like bovine leukemia virus (BLV). Both viruses belong to the same subfamily of retroviruses, harbor a similar genomic organization, infect and transform cells of the hematopoietic system. The main advantage of the BLV system is that it allows direct experimentation in two different species, cattle and sheep. The goal of this review is to present the pathologies associated with BLV in these animals and to summarize the main conclusions which could be helpful to understand HTLV-I-induced leukemogenesis.

Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms