Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Current Trends in Neurology   Volumes    Volume 11 
Dysfunctional neuronal synapses in multiple sclerosis
Karin Schwarz, Frank Schmitz
Pages: 1 - 13
Number of pages: 13
Current Trends in Neurology
Volume 11 

Copyright © 2017 Research Trends. All rights reserved

Multiple sclerosis (MS), a debilitating neuroinflammatory disease of the human central nervous system, is typically considered as a white matter disease in which an auto-reactive immune system attacks components of the axonal myelin sheath to impair fast impulse transmission along myelinated axons in the brain. In the last few years, it has become clear that not only the white matter is affected in multiple sclerosis but also the grey matter and neuronal synapses, the key structures of neuronal communication. These synaptic changes occur early and independent of demyelination processes in the white matter. In this short review, we will summarize results that document an involvement of synapses in multiple sclerosis patients and in rodent models of multiple sclerosis. We discuss how inflammatory signalling in multiple sclerosis can influence synaptic transmission.
View Full Article  


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms