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Trends in Cancer Research   Volumes    Volume 12 
Abstract
Prevention of oxaliplatin-induced neurotoxicity: good vibrations
Gerald M. Higa, Rajesh R. Nair
Pages: 143 - 146
Number of pages: 4
Trends in Cancer Research
Volume 12 

Copyright © 2017 Research Trends. All rights reserved

ABSTRACT
 
Based on current estimates the number of new colorectal cancer diagnoses will exceed one million over the next seven years. More than half of these patients will be treated with a highly active platinum compound called oxaliplatin. While the approved use of oxaliplatin has, for the first time in over 50 years, improved overall survival, the high incidence of oxaliplatin-induced peripheral neuropathy (and the absence of any preventive strategy) limits the clinical utility of this drug. As such, effective prophylaxis against this toxicity should still be considered a priority for innovative prevention research.
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