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Trends in Heterocyclic Chemistry   Volumes    Volume 14 
Abstract
Synthesis of polycyclic rigid molecules by BLOCK assembly employing 3,6-disubstituted-s-tetrazines
Davor Margetić
Pages: 79 - 89
Number of pages: 11
Trends in Heterocyclic Chemistry
Volume 14 

Copyright © 2009 Research Trends. All rights reserved

ABSTRACT
 
A review of cycloaddition reactions of 3,6-disubstituted-1,2,4,5-tetrazines developed to regiospecifically couple together alicyclic reagents, with the particular emphasis on norbornenes. A variety of large polycyclic rigid molecules containing one or more functional groups precisely positioned both in distance and relative orientation onto an inert carbocyclic frame could be effectively produced by s-tetrazine coupling protocol.
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