ABSTRACT Several studies have been reported for the preparation of phenothiazine derivatives; however, some reagents are expensive and require special conditions for handling. In this way, the aim of this research was to synthesize two phenothiazine-steroid derivatives from chlorpromazine. The chemical structure was evaluated through both 1H NMR and 13C NMR spectroscopic analysis. The results showed good yield of the phenothiazine-steroid derivatives. In conclusion in this study, an easy method for the preparation of two phenothiazine-steroid derivatives is reported.
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