ABSTRACT The importance of 2,3-dioxopyrrolidines and related compounds comes from their potent biological activity. This review aims at highlighting the literatures that reported on the structure evidence, preparation, chemical properties and some applications of 2,3-dioxopyrrolidines. It is a trial to attract the attention of the chemists for exploring the synthetic potentialities of 2,3-dioxopyrrolidine derivatives as a key intermediate of the synthesis of new fused heterocycles with a 2,3-dioxopyrrolo moiety for applications in the different branches of applied chemistry.
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