ABSTRACT Useful and efficient methods to introduce stereoselectively nitrogen functions at C-2 in D-ribonolactone chiral templates have been achieved. As application, several non-protein hydroxy-α-amino acids of natural or unnatural origin have been synthesized in good yields, from easily available starting materials. Moreover, some azido- and N-carbamoylamino-derivatives have been prepared and their virtual use as azetidone precursors have been explored.
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