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Trends in Organic Chemistry   Volumes    Volume 3 
Abstract
Stereocontrolled introduction of nitrogen functionalization in D-ribonolactone chiral templates: Synthesis of non-protein amino acids
Jesús Ariza, Josep Font, Rosa M. Ortuño
Pages: 53 - 64
Number of pages: 12
Trends in Organic Chemistry
Volume 3 

Copyright © 1992 Research Trends. All rights reserved

ABSTRACT
 
Useful and efficient methods to introduce stereoselectively nitrogen functions at C-2 in D-ribonolactone chiral templates have been achieved. As application, several non-protein hydroxy-α-amino acids of natural or unnatural origin have been synthesized in good yields, from easily available starting materials. Moreover, some azido- and N-carbamoylamino-derivatives have been prepared and their virtual use as azetidone precursors have been explored.
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