ABSTRACT Development of the synthesis and reaction of heterocyclic compounds by using osganotin reagents is described. Five- and six-membered heterocyclic compounds could be prepared via intramolecular alkylation or C-C bond formation by using organotin ω-halogeno tin species as key intermediates. Moreover, ω-Halogeno tin species could be generated by various tin promoted reaction such as the regioselective ring cleavage of lactones and oxiranes. These methods could be enlarged to characteristic reactions, that is, stereoselective synthesis of heterocycles, ring expansion of lactones, catalytic cycloaddition of oxiranes, and generation of tin enolates to afford C-C bond formation.
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