Effect of geometry and dipole moments on penetrability of fungal wall and fungitoxicity of (5-substituted-8-quinolinolato) (3, 5-diiodosalicylato) copper (II) complexes
Herman Gershon, Muriel Gershon, Donald D. Clarke
Pages: 61 - 64
Number of pages: 4
A quantitative approach was developed for understanding penetrability of a potentially bioactive compound into a target microorganism. It depended on the geometry of the compound and its dipole moment. Bioactivity is manifested upon penetration and non-activity is consistent with exclusion.