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Current Trends in Medicinal Chemistry   Volumes    Volume 4 
Abstract
In vitro interaction of synthesized novel triazinium and iminium salts with some disc antibiotics
C. O. Esimone, U. C. Nwabueze, E. O. Omeje, W. O. Obonga, U. Ajali
Pages: 73 - 78
Number of pages: 6
Current Trends in Medicinal Chemistry
Volume 4 

Copyright © 2006 Research Trends. All rights reserved

ABSTRACT
 
An in vitro interaction study with various disc antibiotics was evaluated for established active (antibacterial) iminium and triazinium salts. The interactions were studied with nine different disc antibiotics of diverse pharmacological class using the overlay-innoculum susceptibility disc method. While the interactions involving Penicillin G and most of the iminium and triazinium salts were synergistic, the antibacterial effect of most of the fluoroquinolones was antagonized by most of the synthesized salts.
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