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Trends in Heterocyclic Chemistry   Volumes    Volume 6 
Abstract
The Strecker reaction on 1-azaadamantan-4-one
I. Iriepa, F. J. Villasante, E. GaIvez-Ruano
Pages: 87 - 95
Number of pages: 9
Trends in Heterocyclic Chemistry
Volume 6 

Copyright © 1999 Research Trends. All rights reserved

ABSTRACT
 
The different behaviour of the 1-azatricyclo[3.3.1.13,7]decan-4-one (1-azaadamantan-4-one, 1) in several modifications of the classical Strecker reaction has been studied. A method is described for the synthesis of the 4α-cyano-4β-hydroxy-1-azatricyclo[3.3.1.13,7]decane (2) and for the synthesis of 4β-amino-4α-cyano-1-azatricyclo[3.3.1.13,7]decane (7). The compounds synthesized have been studied by NMR spectroscopy, IR spectroscopy and mass spectrometry.
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