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Current Topics in Peptide & Protein Research   Volumes    Volume 7 
Clinical effect of conjugated caseinate, FP-10, in controlling intragastric H. pylori status in asymptomatic carriers
Takashi Inoue, Hiroshi Nakano, Hidehiko Beppu, Kaoru Kawai, Koji Suzuki, Kan Shimpo, Shigeru Sonoda
Pages: 35 - 40
Number of pages: 6
Current Topics in Peptide & Protein Research
Volume 7 

Copyright © 2005 Research Trends. All rights reserved


Helicobacter pylori (H. pylori) infection is a public concern due to its prevalence, pathogenicity and carcinogenicity. In order to prevent disease onset, it is important to control intragastric H. pylori status. FP-10 is a conjugated caseinate that inhibits bacterial adhesion to gastric mucosa. We determined the effects of FP-10 administration (1.0 g/day, 12 weeks) in asymptomatic H. pylori carriers. Mean 13C urea breath test values decreased significantly with FP-10 administration. There were no severe or persistent adverse events during the administration period. Therefore, FP-10 administration is considered to reduce intragastric H. pylori safely and effectively.

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