A high yielding synthetic method for the selective deprotection of S-acetyl group in N, S-bis acylated L-cysteinyl Amides
Vivekananda Reddy Mothukuri, G. C. M. Kondaiah, Rakeshwar Bandichhor, V. M. Gurav
Pages: 39 - 40
Number of pages: 2
A mild method for the deprotection of thioacetyl is described. Selective deprotection of –SAc in N, S-bis acylated cysteinyl amides using LiOH/MeOH/THF/H2O at 10oC for 20-30 min afforded N-acetylated cysteinyl amides.